A patient with polymyositis presents with proximal muscle weakness. Which autoantibody is most specific?

A patient with polymyositis presents with proximal muscle weakness. Which autoantibody is most specific?

  • Correct Answer: Anti-Jo-1
  • Anti-CCP
  • Anti-dsDNA
  • Anti-Smith

Explanation: Anti-Jo-1 is specific for polymyositis indicating myositis-associated lung disease.

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