Exon skipping is an example of what type of splicing?
- Correct Answer: alternative
- comprehensive
- inclusive
- proactive
Explanation: One example of alternative splicing is with exon skipping. The D. melanogaster (fruit fly) doublesex (dsx) gene is involved in the fly's determination system. Pre-mRNAs from this gene contain 6 eons, numbered 1-6. In males, exons 1,2,3,5,and 6 are spliced together to form the mRNA, which encodes a transcriptional regulatory protein required for male development. In females, exons 1, 2, 3, and 4 are joined, and a polyadenylation signal in exon 4 causes cleavage of the mRNA at that point. The resulting mRNA is a transcriptional regulatory protein required for female development.
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